Lj-1-60

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 3270

CAS [2414269-68-2]

MF C17H15BrO4
MW 363.20

  • Purity: 99%
  • Soluble in DMSO
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Lj-1-60

Description

Lj-1-60 is an ATP-competitive inhibitor targeting Fyn protein kinase. Lj-1-60 inhibited melanoma proliferation and induced cell cycle arrest into the G2/M phase and apoptosis by targeting Fyn/Stat3 pathway. Lj-1-60 markedly reduced cell viability in a time- and dose-dependent manner, with IC50 values of 1.65 µM (Sk-Mel-5) and 1.36 µM (Sk-Mel-28), respectively. Also, the IC50 value of Lj-1-60 in melanocyte cells PIG1 was 3.9 µM.

KEYWORDS: Lj-1-60 | supplier | Fyn inhibitor | Lj1-60 | Lj 1-60 | CAS [2414269-68-2] | Non Selective | SRC | Inhibitor | Enzymes

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10 mg €90.00 In Stock
50 mg €270.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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