Mitochonic acid 5 (MA-5) is a mitochondrial drug. MA-5 acts via the MAPK-ERK-Yap signaling pathway, which increases Bnip3-related mitophagy, leading to suppressed apoptotic signaling following the inflammatory response. MA-5 can protect mitochondrial function by regulating energy metabolism and reducing mitochondrial oxidative stress. Mitochonic acid 5 increased ATP, rescued mitochondrial disease fibroblasts and prolonged the life span of the disease model “Mitomouse”.

KEYWORDS: Mitochonic acid 5 | supplier | Mitochondrial drug | MA-5 | MA 5 | MA5 | CAS [1354707-41-7] | MAPK | MAPK (p38) | Activator | Enzymes | Mitochondrial disease