Mitochonic acid 5 - MA-5

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 3197

CAS [1354707-41-7]

MF C18H13F2NO3
MW 329.30

  • Purity: 98%
  • Soluble in 0.1N NaOH(aq) and DMSO

Mitochonic acid 5


Mitochonic acid 5 (MA-5) is a mitochondrial drug. MA-5 acts via the MAPK-ERK-Yap signaling pathway, which increases Bnip3-related mitophagy, leading to suppressed apoptotic signaling following the inflammatory response. MA-5 can protect mitochondrial function by regulating energy metabolism and reducing mitochondrial oxidative stress. Mitochonic acid 5 increased ATP, rescued mitochondrial disease fibroblasts and prolonged the life span of the disease model “Mitomouse”.

KEYWORDS: Mitochonic acid 5 | supplier | Mitochondrial drug | MA-5 | MA 5 | MA5 | CAS [1354707-41-7] | MAPK | MAPK (p38) | Activator | Enzymes | Mitochondrial disease

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5 mg €90.00 In Stock
25 mg €300.00 In Stock
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2 x 5 mg €140.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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