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MK-4482
- EIDD-2801 - Molnupiravir
- Optical Purity: Optically pure
- Soluble in water and DMSO
- MF: C13H19N3O7
- MW: 329.31
Description
MK-4482 (EIDD-2801) is a potent and orally bioavailable broad-spectrum antiviral drug under investigation. It is a modified version of its active nucleoside analog EIDD-1931 with an improved drug profile. In mice infected with SARS-CoV or MERS-CoV, both prophylactic and therapeutic administration of MK-4482 improved pulmonary function and reduced virus titer and body weight loss.
More Information
| Parent CAS No. | 2349386-89-4 |
|---|---|
| Chemical Name | ((2R,3S,4R,5R)-3,4-Dihydroxy-5-(4-(hydroxyamino)-2-oxopyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl isobutyrate |
| SMILES | C1(=O)N/C(=N/O)/C=CN1[C@@H]1O[C@H](COC(=O)C(C)C)[C@@H](O)[C@H]1O |&1:9,11,19,21,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C13H19N3O7/c1-6(2)12(19)22-5-7-9(17)10(18)11(23-7)16-4-3-8(15-21)14-13(16)20/h3-4,6-7,9-11,17-18,21H,5H2,1-2H3,(H,14,15,20)/t7-,9-,10-,11-/m1/s1 |
| InChiKey | HTNPEHXGEKVIHG-QCNRFFRDSA-N |
| CID | 145996610 |
| Short Description | Antiviral agent |
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