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Crisaborole
- AN2728
- Soluble in DMSO
- MF: C14H10BNO3
- MW: 251.05
Description
Crisaborole is a potent inhibitor of PDE4 (IC50 value of 0.49 μM) and inflammation-related cytokine release in vitro and in vivo. Anti-inflammatory agent.
More Information
| Parent CAS No. | 906673-24-3 |
|---|---|
| Chemical Name | 4-(1-Hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-5-yloxy)benzonitrile |
| SMILES | O(C1C=CC(C#N)=CC=1)C1=CC=C2B(O)OCC2=C1 |
| MFCD | MFCD17169940 |
| InChi | InChI=1S/C14H10BNO3/c16-8-10-1-3-12(4-2-10)19-13-5-6-14-11(7-13)9-18-15(14)17/h1-7,17H,9H2 |
| InChiKey | USZAGAREISWJDP-UHFFFAOYSA-N |
| CID | 44591583 |
| Short Description | PDE4 inhibitor |
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