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Axon 2963

CAS [1451272-71-1]

MF C13H12ClN3O4S
MW 341.77

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO



SBI-425 is a potent, selective and oral bioavailable inhibitor of tissue-nonspecific alkaline phosphatase (TNAP) with an IC50 value of 0.016 μM. SBI-425 robustly inhibits TNAP in vivo after oral dosing. Furthermore, SBI-425 demonstrated activity in blocking calcification in patient derived fibroblasts as well as in rodent models of GACI and PXE.

KEYWORDS: SBI-425 | supplier | TNAP inhibitor | SBI425 | SBI 425 | CAS [1451272-71-1] | Non Selective (Tyrosine Specific Phosphomonoesters) | Alkaline Phosphatase | Inhibitor | Enzymes | ALPL

Size Unit Price Stock
10 mg €125.00 In Stock
50 mg €425.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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