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Axon 2838
CAS [654080-02-1]
MF C29H31NO6MW 489.56
SK-216 is a specific inhibitor of PAI-1 and limits tumor progression and angiogenesis. SK-216 could suppress PAI-1 expression in rat colon cancer cells as well as intestinal polyp formation in a Min mouse. Furthermore, SK-216 could inhibit lung metastasis of human lung cancer cells and mouse melanoma cells in an intravenously-injected mouse mode. Potential novel anti-metastasis agent for human osteosarcoma.
KEYWORDS: SK-216 | supplier | PAI-1 inhibitor | SK216 | SK 216 | CAS [654080-02-1] | [654080-03-2] | Serpin | Plasminogen activator inhibitor-1 (PAI-1) | Inhibitor | Enzymes
2-(5-(6-(5-tert-Butylbenzo[d]oxazol-2-yl)naphthalen-2-yloxy)pentyl)malonic acid
[654080-02-1]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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