Based on 5 reference(s) in Google Scholar 8 10 5

Axon 2838

CAS [654080-02-1]

MF C29H31NO6
MW 489.56

  • Purity: 98%
  • Soluble in 0.1N NaOH(aq) and DMSO



SK-216 is a specific inhibitor of PAI-1 and limits tumor progression and angiogenesis. SK-216 could suppress PAI-1 expression in rat colon cancer cells as well as intestinal polyp formation in a Min mouse. Furthermore, SK-216 could inhibit lung metastasis of human lung cancer cells and mouse melanoma cells in an intravenously-injected mouse mode. Potential novel anti-metastasis agent for human osteosarcoma.

KEYWORDS: SK-216 | supplier | PAI-1 inhibitor | SK216 | SK 216 | CAS [654080-02-1] | [654080-03-2] | Serpin | Plasminogen activator inhibitor-1 (PAI-1) | Inhibitor | Enzymes

Size Unit Price Stock
5 mg €105.00 In Stock
25 mg €365.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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