Based on 2 reference(s) in Google Scholar 8 10 2

Axon 2816

CAS [1415262-07-5]

MF C18H16N4O2
MW 320.35

  • Purity: 99%
  • Soluble in DMSO



WX-132-18B is a microtubule-depolymerizing agent that selectively acts on the colchicine-binding site of tubulin and exerts potent in vitro and in vivo anti-tumor effects. Specifically, WX-132-18B exhibited high in vitro cytotoxic activity (GI50 value of 1.9–3.2 nM), significant potency against tubulin assembly (IC50 value of 0.77 μM), and substantial inhibition of colchicine binding (99% at 5 μM). Moreover, WX-132-18B caused cell arrest in G2/M phase.

KEYWORDS: WX-132-18B | Supplier | Microtubule inhibitor | WX132-18B | WX 132-18B | CAS [1415262-07-5] | Cytoskeleton | Tubulin | Inhibitor | Proteins | Colchicine | G2/M phase

Size Unit Price Stock
5 mg €115.00 In Stock
25 mg €395.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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