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Featured Products
Axon 2812
CAS [1846570-31-7]
MF C28H38N4O3MW 478.63
CM-272 is a first-in-class potent, selective and reversible inhibitor of histone methyltransferase G9a and DNA-methyltransferase 1 with IC50 values of 8nM and 382 nM, respectively. CM-272 inhibits cell proliferation and promotes apoptosis, inducing interferon-stimulated genes and immunogenic cell death. Moreover, CM-272 significantly prolongs survival of AML, ALL and DLBCL xenogeneic models.
KEYWORDS: CM-272 | Supplier | G9a/DNMT inhibitor | CM272 | CM 272 | CAS [1846570-31-7] | CAS [1846570-32-8] | Histone | HMTase | Inhibitor | Enzymes | Haematological tumour | Haematological neoplasia | Hepatocellular carcinoma
6-Methoxy-2-(5-methylfuran-2-yl)-N-(1-methylpiperidin-4-yl)-7-(3-(pyrrolidin-1-yl)propoxy)quinolin-4-amine
[1846570-31-7]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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