Based on 4 reference(s) in Google Scholar 8 10 4

Axon 2812

CAS [1846570-31-7]

MF C28H38N4O3
MW 478.63

  • Purity: 98%
  • Soluble in 0.1N HCl(aq) and DMSO



CM-272 is a first-in-class potent, selective and reversible inhibitor of histone methyltransferase G9a and DNA-methyltransferase 1 with IC50 values of 8nM and 382 nM, respectively. CM-272 inhibits cell proliferation and promotes apoptosis, inducing interferon-stimulated genes and immunogenic cell death. Moreover, CM-272 significantly prolongs survival of AML, ALL and DLBCL xenogeneic models.

KEYWORDS: CM-272 | Supplier | G9a/DNMT inhibitor | CM272 | CM 272 | CAS [1846570-31-7] | CAS [1846570-32-8] | Histone | HMTase | Inhibitor | Enzymes | Haematological tumour | Haematological neoplasia | Hepatocellular carcinoma

Size Unit Price Stock
5 mg €130.00 In Stock
25 mg €460.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €220.00 In Stock
2 x 25 mg €760.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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