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Axon 2790
CAS [56632-39-4]
MF C21H17NO3MW 331.36
BHPI is a potent noncompetitive ERα inhibitor that selectively blocks proliferation of drug-resistant ERα-positive breast and ovarian cancer cells (IC50 values of 27 and 15 nM in MDA-468 and T47D cell lines, respectively). Moreover, BHPI induced rapid and substantial tumor regression in a mouse xenograft model of breast cancer.
KEYWORDS: BHPI | supplier | ER-α antagonist | CAS [56632-39-4] | Estrogen | Estrogen (ER) | Antagonist | Receptors | Breast cancer
3,3-Bis(4-hydroxyphenyl)-7-methylindolin-2-one
[56632-39-4]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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