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5 mg

$99.00

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2 x 25 mg $594.00 $484.00 In stock

GTX-758

Name: GTX-758
SKU: 4369

Axon 4369

CAS: 938067-78-8

Purity: 99%

Soluble in DMSO and EtOH

MF: C19H13F2NO3
MW: 341.31

Description

GTX-758 is a selective and orally active estrogen receptor α (ER-α) agonist. GTX-758 induces sex hormone binding globulin (SHBG) and subsequently reduces free testosterone (FT) to levels below that achieved with LHRH agonists.

More Information

Certificate of Analysis (B1)

Material Safety Data Sheet (B1)

Estrogen (ER)

Parent CAS No. 938067-78-8

Chemical Name N-4-Fluorophenyl-N-4-hydroxyphenyl3-fluoro-4-hydroxybenzamide

SMILES C1(F)=CC(C(N(C2=CC=C(O)C=C2)C2=CC=C(F)C=C2)=O)=CC=C1O

MFCD N.A.

InChi InChI=1S/C19H13F2NO3/c20-13-2-4-14(5-3-13)22(15-6-8-16(23)9-7-15)19(25)12-1-10-18(24)17(21)11-12/h1-11,23-24H

InChiKey FBCQEUMZZNVQKD-UHFFFAOYSA-N

CID 46861578

Short Description ER-α agonist

GTX-758 ER-α agonist GTX 758 GTX758 Capesaris CAS 938067-78-8 Axon Medchem Axon 4369 Estrogen Estrogen (ER) Agonist Receptors CRPC ADT Castration-resistant prostate cancer Supplier Vendor

References

MS Steiner et al. GTX-758, An Oral ERa Agonist, Increases Sex Hormone Binding Globulin, Reduces Free T and Decreases PSA in Patients with Castration Resistant Prostate Cancer. Annals of Oncology, Volume 23, ix304.

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GTX-758

Description

More Information

References

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Axon Ligands™ for Cell Signaling & Oncology

Axon Ligand™ for Stem Cell Research

Axon Ligands™ for Epigenetic Research

Parent CAS No.	938067-78-8
Chemical Name	N-4-Fluorophenyl-N-4-hydroxyphenyl3-fluoro-4-hydroxybenzamide
SMILES	C1(F)=CC(C(N(C2=CC=C(O)C=C2)C2=CC=C(F)C=C2)=O)=CC=C1O
MFCD	N.A.
InChi	InChI=1S/C19H13F2NO3/c20-13-2-4-14(5-3-13)22(15-6-8-16(23)9-7-15)19(25)12-1-10-18(24)17(21)11-12/h1-11,23-24H
InChiKey	FBCQEUMZZNVQKD-UHFFFAOYSA-N
CID	46861578
Short Description	ER-α agonist

AXON ID	NAME	DESCRIPTION	FROM PRICE
1231	PPT	ER-α agonist	From $104.50
1926	Estetrol	Estrogen receptor agonist (four- to five-fold preference for the Erα)	From $154.00
2790	BHPI	ER-α antagonist	From $137.50
3320	Diethylstilbestrol	Estrogen receptor agonist	From $55.00