HIF-2a Translation Inhibitor 76

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 2614

CAS [882268-69-1]

MW 287.32

  • Purity: 99%
  • Soluble in DMSO

HIF-2a Translation Inhibitor 76


HIF-2a translation inhibitor (IC50 value 5 µM); Decreases HIF-2a protein and HIF-2a target gene expression in normoxia and hypoxia independent of HIF-2a mRNA expression or HIF-2a protein stability, and independent of mTOR activity. Moreover, the translation inhibitor 76 enhances binding of IRP1 to the HIF-2a IRE (Iron-Responsive Element).

KEYWORDS: HIF-2a Translation Inhibitor 76 | supplier | HIF2a translation inhibitor | CAS [882268-69-1] | DNA-RNA | HIF-2α | Transcription Factor | Iron-Responsive Element | IRE | mTOR | hypoxia | IRP1

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5 mg €70.00 In Stock
25 mg €185.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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