NVP-TNKS656 - TNKS 656

Based on 24 reference(s) in Google Scholar 8 10 24

Axon 2599

CAS [1419949-20-4]

MF C27H34N4O5
MW 494.58

  • Purity: 99%
  • Soluble in DMSO

NVP-TNKS656

Description

Highly potent, selective and orally active tankyrase inhibitor and antagonist of Wnt pathway activity in the MMTV-Wnt1 mouse xenograft model (IC50 values 0.0155 µM and 0.0060 µM for TNKS1 and TNKS2, respectively and >5000-fold selectivity over PARP1 and PARP2).

KEYWORDS: NVP-TNKS656 | Supplier | Wnt/TNKS inhibitor | TNKS 656 | NVP-TNKS 656 | NVPTNKS656 | TNKS656 | CAS [1419949-20-4] | DNA-RNA | TNKS1 | TNKS2 | PARP | Wnt | XAV939 | KRAS-mutant

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Size Unit Price Stock
2 mg €95.00 In Stock
5 mg €145.00 In Stock
25 mg €535.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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