Based on 31 reference(s) in Google Scholar 9 10 31

Axon 2567

CAS [932986-18-0]

MW 308.83

  • Purity: 99%
  • Soluble in DMSO



Small-molecule modulator of the unfolded protein response (UPR) with antidiabetic activity (IC50 value 8.826 µM for azoramide-induced increase of ASGR-Cluc secretion in HuH7 cells). Azoramide is a dual-function ER modulator that improves ER protein-folding ability and activates ER chaperone capacity to protect cells against ER stress. Moreover, Azoramide improves insulin sensitivity and pancreatic β-cell function in multiple obese mouse preclinical models.

KEYWORDS: Azoramide | supplier | UPR modulator | CAS [932986-18-0] | Unfolded Protein Response | endoplasmatic reticulum | ER stress | protein folding | PERK | IRE1 | ATF6 | obesity | antidiabetic | glucose

Size Unit Price Stock
10 mg €65.00 In Stock
50 mg €215.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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