SR 3576

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 2365

CAS [1164153-22-3]

MF C27H27N5O5
MW 501.53

SR 3576

Description

Very potent JNK3 inhibitor (IC50 value 7 nM) with >2800-fold selectivity over p38 (p38 IC50 value >20 μm) and a cell-based potency of ca. 1 μM.

Apoptosis Cell Signaling & Oncology Immunology Pain & Inflammation MAPK (JNK) p53-Tumor Suppression NF-κB MAPK EC 2.7.11.24

Very potent JNK3 inhibitor with >2800-fold selectivity over p38

3-(4-(3-m-tolylureido)-1H-pyrazol-1-yl)-N-(3,4,5-trimethoxyphenyl)benzamide

[1164153-22-3]

Order

Size	Unit Price	Stock
10 mg	€135.00	In Stock
50 mg	€530.00	In Stock

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Axon ID	Name	Description
1291	AEG 3482	JNK inhibitor	€90.00
2002	Bentamapimod	JNK inhibitor, which inhibited JNK1, JNK2 and JNK3	€70.00
2025	CC-401	ATP-competitive JNK inhibitor	€120.00
2361	JNK-IN-8	Remarkably potent and selective covalent inhibitor of JNK	€95.00
2519	SP 600125	Selective, reversible, and ATP-competitive JNK inhibitor	€70.00
2634	CC-930	Potent, selective, and orally active anti-fibrotic JNK inhibitor	€95.00
2949	JNK inhibitor VIII	Selective, ATP-competitive, and cell-permeable JNK inhibitor	€105.00
3625	GNE-3511	Potent, selective, orally bioavailable and brain-penetrant DLK inhibitor	€90.00