BAY 57-1293 - Pritelivir | AIC 316

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 2266

CAS [348086-71-5]

MF C18H18N4O3S2
MW 402.49

  • Purity: 99%
  • Soluble in DMSO

BAY 57-1293

Description

Potent helicase-primase inhibitor (HPI) effective against herpes simplex virus (HSV) infections with IC50 value of 20 nM for inhibition of the replication of both HSV-1 and HSV-2 in Vero cells, and ED50 value of 0.5 mg/kg for both HSV-1 and HSV-2 in the murine lethal challenge model of disseminated herpes. BAY 57-1293 in vivo was found to be superior compared to all compounds currently used to treat HSV infections, and is active also against acyclovir-resistant mutant strains which carry mutations in the tk or DNA pol genes.
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5 mg €80.00 In Stock
25 mg €240.00 In Stock
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2 x 5 mg €120.00 In Stock
2 x 25 mg €360.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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