STF 118804

Based on 12 reference(s) in Google Scholar 9 10 12

Axon 2253

CAS [894187-61-2]

MF C25H23N3O4S
MW 461.53

  • Purity: 98%
  • Soluble in DMSO

STF 118804


Highly specific, next-generation NAMPT inhibitor, that reduces the viability of most B-ALL cell lines with high potency demonstrating IC50 values in the low nanomolar range, and improves survival in an orthotopic xenotransplant model of high-risk acute lymphoblastic leukemia. Additionally, STF 118804 induces leukemia cell apoptosis without antecedent cell cycle arrest, and targets leukemia stem cells.

KEYWORDS: STF 118804 | supplier | NAMPT inhibitor | STF118804 | CAS [894187-61-2] | Nicotinamide D-ribonucleotide | NAD | NAD+ | apoptosis | leukemia | cell cycle | arrest | stem cells

Size Unit Price Stock
10 mg €120.00 In Stock
50 mg €450.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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