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GNI-50
- SBI796768
Axon 3952
CAS:
1363154-45-3
Purity:
98%
- Soluble in 0.1N HCl(aq) and DMSO
- MF: C19H22N4O4S
- MW: 402.47
Description
GNI-50 is an orally active NAMPT inhibitor which exhibited excellent biochemical and cellular (A2780) potency with IC50 values of 0.007 μM and 0.032 μM, respectively. GNI-50 also showed excellent in vivo antitumor efficacy when dosed orally in an A2780 ovarian tumor xenograft model.
More Information
| Parent CAS No. | 1363154-45-3 |
|---|---|
| Chemical Name | 1-(4-(8-Oxa-3-azabicyclo[3.2.1]octan-3-ylsulfonyl)phenyl)-3-(pyridin-3-ylmethyl)urea |
| MFCD | N.A. |
| Short Description | NAMPT inhibitor |
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