INCB 024360-analog - IDO inhibitor 5l

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 2215

CAS [914471-09-3]

MF C9H7ClFN5O2
MW 271.64

  • Purity: 99%
  • Soluble in DMSO

INCB 024360-analog

Description

Potent competitive inhibitor of indoleamine 2,3-dioxygenase (IDO1, IC50 value 67 nM) with in vivo pharmacodynamic activity and efficacy in a mouse melanoma model; This INCB024360-analog decreased kynurenine levels by >50% in plasma and inhibited B16-GM-CSF tumor growth in a dose dependent fashion.

INCB 024360 (or Epacadostat; Axon 1733) is available from Axon Medchem as well.

Order
Size Unit Price Stock
5 mg €85.00 In Stock
25 mg €255.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €120.00 In Stock
2 x 25 mg €360.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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