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10 mg

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GNF-PF-3777

Name: GNF-PF-3777
SKU: 3597

- 8-Nitrotryptanthrin

Axon 3597

CAS: 77603-42-0

Purity: 99%

Soluble in DMSO

MF: C15H7N3O4
MW: 293.23

Description

GNF-PF-3777 is a potent hIDO2 inhibitor with a Ki value of 0.97 μM.

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Certificate of Analysis (B1)

Material Safety Data Sheet (B1)

Parent CAS No.	77603-42-0
Chemical Name	8-Nitroindolo[2,1-b]quinazoline-6,12-dione
MFCD	MFCD00618023
Short Description	hIDO2 inhibitor

GNF-PF-3777 hIDO2 inhibitor 8-Nitrotryptanthrin GNF-PF3777 GNF-PF 3777 CAS 77603-42-0 Axon Medchem Axon 3597 L-Kynurenine IDO Inhibitor Enzymes Human IDO2 Tryptanthrin AhR Indoleamine 2 3-dioxygenase-2 Supplier Vendor

References

J Li et al. Establishment of a human indoleamine 2, 3-dioxygenase 2 (hIDO2) bioassay system and discovery of tryptanthrin derivatives as potent hIDO2 inhibitors. Eur J Med Chem. 2016 Nov 10;123:171-179.

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GNF-PF-3777

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