PF 4693627 - PF 04693627

Based on 14 reference(s) in Google Scholar 8 10 14

Axon 2020

CAS [1312815-93-2]

MF C26H29Cl2N3O3
MW 502.43

  • Purity: 100%
  • Optical purity: d.e. >98%
  • Soluble in DMSO

PF 4693627

Description

Potent, selective and orally bioavailable inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1) for the potential treatment of inflammation (IC50 value 3 nM and 109 nM in enzyme assay and WHB assay respectively). PF 4693627 shows excellent in vitro and in vivo properties and is selective against relevant human enzymes COX-2, TXAS, PGDS, 5-LOX, 15-LOX and 12-LOX.
Order
Size Unit Price Stock
5 mg €125.00 In Stock
25 mg €425.00 In Stock
Need more? Bulk Inquiry

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

Please wait...