CX 4945 hydrochloride - Silmitasertib hydrochloride

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1965

CAS [2108312-01-0]

MF C19H12ClN3O2.HCl
MW 386.23

Purity: 98%
Soluble in 0.1N NaOH(aq) and DMSO

CX 4945 hydrochloride

Description

Orally available, potent and selective casein kinase 2 (CK2) inhibitor

A Siddiqui-Jain et al. CX-4945, an Orally Bioavailable Selective Inhibitor of Protein Kinase CK2, Inhibits Prosurvival and Angiogenic Signaling and Exhibits Antitumor Efficacy. Cancer Res. 2010, 70, 10288-10298.

AD Ferguson et al. Structural basis of CX-4945 binding to human protein kinase CK2. FEBS Lett. 2011, 585(1), 104-110.

F Pierre et al. Pre-clinical characterization of CX-4945, a potent and selective small molecule inhibitor of CK2 for the treatment of cancer. Mol. Cell Biochem. 2011, 356(1-2), 37-43.

Inhibitor of Casein kinase 2 (CK2)

Chemical name

5-(3-chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid hydrochloride

Parent CAS No.

[1009820-21-6]

Order

Size	Unit Price	Stock
5 mg	€90.00	In Stock
25 mg	€300.00	In Stock

Special Offers

Size	Unit Price	Stock
2 x 5 mg	€140.00	In Stock
2 x 25 mg	€460.00	In Stock

Need more? Bulk Inquiry

Related Products

Axon ID	Name	Description	From price
3279	CKI-7 dihydrochloride	Selective inhibitor of Casein kinase 1		€120.00
2717	Apigenin	Selective inhibitor of Casein kinase 2 (CK2)		€70.00

Customer Support

Customer Services

About Axon Medchem

Contact Us

CX 4945 hydrochloride - Silmitasertib hydrochloride

Description

Chemical name

Parent CAS No.

Customer Support

About Axon Medchem

Download Product Catalog

Follow Us

Customer Support

Customer Services

About Axon Medchem

Contact Us

CX 4945 hydrochloride - Silmitasertib hydrochloride

Description

Chemical name

Parent CAS No.

Related Products

Customer Support

About Axon Medchem

Download Product Catalog

Follow Us

Send us a message

Contact Us