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PDE5 inhibitor 42

Axon 1709
CAS:  936449-28-4
Purity:  98%
  • Soluble in DMSO
  • MF:  C23H31N7O3
  • MW:  453.54

Description

Potent and selective phosphodiesterase type 5 (PDE5) inhibitor (IC50: 0.04 nM); PDE6/PDE5 and PDE11/PDE5 ratios to be 100x and 530x respectively; a second generation PDE5 inhibitor under investigation

More Information

Parent CAS No. 936449-28-4
Chemical Name 1-(1-(2-ethoxyethyl)-3-ethyl-7-(4-methylpyridin-2-ylamino)-1H-pyrazolo[4,3-d]pyrimidin-5-yl)piperidine-4-carboxylic acid
SMILES N1C(NC2N=CC=C(C)C=2)=C2N(CCOCC)N=C(CC)C2=NC=1N1CCC(C(O)=O)CC1
MFCD N.A.
InChi InChI=1S/C23H31N7O3/c1-4-17-19-20(30(28-17)12-13-33-5-2)21(25-18-14-15(3)6-9-24-18)27-23(26-19)29-10-7-16(8-11-29)22(31)32/h6,9,14,16H,4-5,7-8,10-13H2,1-3H3,(H,31,32)(H,24,25,26,27)
InChiKey IQZQWPRZFLHJFI-UHFFFAOYSA-N
CID 16066664
Short Description PDE5 inhibitor

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