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Digoxin
- Digitalis
Axon 1649
CAS:
20830-75-5
Purity:
98%
- Soluble in DMSO
- MF: C41H64O14
- MW: 780.94
Description
Digoxin is a successful medication in the treatment of irregular heart rhythms, namely atrial fibrillation, atrial flutter and sometimes heart failure that cannot be controlled by other medication.
Digoxin is also used as a standard control substance to test for p-glycoprotein inhibition. Recent studies show that digoxin acts as inhibitor of HIF-1α synthesis, reduces protein levels and thus slows tumor growth in mice.
Digoxigenin bisdigitoxoside (Axon 1695) is also available as a metabolite of Digoxin.
More Information
| Parent CAS No. | 20830-75-5 |
|---|---|
| Chemical Name | 4-((3S,5R,8R,9S,10S,12R,13S,14S,17R)-3-((2R,4S,5S,6R)-5-((2S,4S,5S,6R)-5-((2S,4S,5S,6R)-4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-4-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-4-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-12,14-dihydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-17-yl)furan-2(5H)-one |
| MFCD | MFCD00003674 |
| Short Description | HIF-1 inhibitor |
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