Digoxin - Digitalis

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1649

CAS [20830-75-5]

MF C41H64O14
MW 780.94

  • Purity: 98%
  • Soluble in DMSO

Digoxin

Description

Digoxin is a successful medication in the treatment of irregular heart rhythms, namely atrial fibrillation, atrial flutter and sometimes heart failure that cannot be controlled by other medication.
Digoxin is also used as a standard control substance to test for p-glycoprotein inhibition. Recent studies show that digoxin acts as inhibitor of HIF-1α synthesis, reduces protein levels and thus slows tumor growth in mice

Na+/K+ ATPase pump inhibitor

Chemical name

4-((3S,5R,8R,9S,10S,12R,13S,14S,17S)-3-((2R,4S,5S,6R)-5-((2S,4S,5S,6R)-5-((2S,4S,5S,6R)-4,5-dihydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-4-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-4-hydroxy-6-methyltetrahydro-2H-pyran-2-yloxy)-12,14-dihydroxy-10,13-

Parent CAS No.

[20830-75-5]

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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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