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GDC 0449 - Vismodegib | HhAntag 691

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1500

CAS [879085-55-9]

MF C19H14Cl2N2O3S
MW 421.30

  • Purity: 99%
  • Soluble in DMSO

GDC 0449

Description

The first-in-class inhibitor of Hedgehog (Hh) signaling pathway; more specifically, an orally bioavailable and potent inhibitor of smoothened homologue (SMO); an investigational anti-cancer drug for Medulloblastoma, advanced basal cell skin cancer etc
Order
Size Unit Price Stock
5 mg €70.00 In Stock
25 mg €200.00 In Stock
Special Offers
Size Unit Price Stock
2 x 5 mg €100.00 In Stock
2 x 25 mg €280.00 In Stock
Need more? Bulk Inquiry

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2027 PF 5274857 hydrochloride Smoothened (SMO) antagonist €95.00
2196 LY 2940680 Small-molecule antagonist of the Smoothened (SMO) receptor €120.00
2356 BMS 833923 Oral antagonist of the Hedgehog signaling component Smoothened (SMO) €75.00
2325 WAY 316606 hydrochloride Potent inhibitor of sFRP-1 that stimulates Wnt signaling €85.00
2642 GANT61 Inhibitor of GLI-mediated transcription and Hedgehog (Hh) signaling €120.00
2654 JK184 Hedgehog (Hh) signaling pathway antagonist with antiproliferative activity €80.00

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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