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Eplivanserin
- SR 46349B
- Parent CAS: 130579-75-8
- Soluble in DMSO
- MF: C19H21FN2O2.0.5C4H4O4
- MW: 386.42
Description
More Information
| Parent CAS No. | 130579-75-8 |
|---|---|
| Chemical Name | (E)-1-(2-Fluoro-phenyl)-3-(4-hydroxy-phenyl)-propenone O-(2-dimethylamino-ethyl)-oxime hemi-fumarate |
| SMILES | C1C=CC(F)=C(/C(=NOCCN(C)C)/C=C/C2C=CC(O)=CC=2)C=1.C(/C(O)=O)=CC(O)=O |
| MFCD | MFCD00893361 |
| InChi | InChI=1S/2C19H21FN2O2.C4H4O4/c2*1-22(2)13-14-24-21-19(17-5-3-4-6-18(17)20)12-9-15-7-10-16(23)11-8-15;5-3(6)1-2-4(7)8/h2*3-12,23H,13-14H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b2*12-9+,21-19-;2-1+ |
| InChiKey | RNLKLYQQDLHHBH-ABDBJYMXSA-N |
| CID | 135854444 |
| Short Description | 5-HT2A antagonist |
References
- M. Rinaldi-Carmona et al. Biochemical and Pharmacological Properties of SR 46349B, a New Potent and Selective 5-Hydroxytryptamine2 Receptor Antagonist. JPET 1992, 262(2), 759-768.
- F Chaouloff et al. Repeated DOI and SR 46349B treatments do not affect elevated plus-maze anxiety despite opposite effects on cortical 5-HT2A receptors. Eur. J. Pharmacol. 1997, 334(1), 25-29.
- BR Teergarden et al. 5-HT2A Inverse-Agonists for the Treatment of Insomnia. Current Topics Med. Chem. 2008, 8(11), 969–976.
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