RO 28-1675 - RO 28-0450, (R)-

Based on 20 reference(s) in Google Scholar 80 100 20

Axon 1356

CAS [300353-13-3]

MF C18H22N2O3S2
MW 378.51

RO 28-1675

Description

Glucokinase GK activator; more active R-enantiomer of RO-28-0450 (Axon 1134) in comparison with S-enantiomer, RO 28-1674 (Axon 1355)

Cell Signaling & Oncology Diabetes & Metabolism Glucokinase EC 2.7.1.2

Glucokinase (GK) activator

(R)-(-)-3-Cyclopentyl-2-(4-methanesulfonyl-phenyl)-N-thiazol-2-yl-propionamide

[300353-13-3]

Order

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Axon ID	Name	Description
1134	RO 28-0450	Glucokinase (GK) activator	€125.00
1355	RO 28-1674	Glucokinase (GK) activator	€125.00
1821	CCT 007093	Protein phosphatase 1D (PPM1D) inhibitor	€95.00
2149	Mitapivat	Activator of pyruvate kinase isoenzyme M2 (PKM2)	€110.00
2175	3PO	Inhibitor of HIF-1-induced PFKFB3, an enzyme with a key role in glycolysis.	€65.00
2178	BCI	Allosteric inhibitor of dual-specificity phosphatases (DUSP)	€75.00
2240	TEPP-46	Potent activator of recombinant PKM2 with little or no activity versus PKM1, PKL and PKR.	€90.00
2263	Tacrolimus	Potent Calcineurin (Ca2+ dependent protein phosphatase 2B) inhibitor	€100.00
2186	SF 1670	Inhibitor of PTEN with significant inhibitory effect on PTPRC and GALK	€120.00
2542	PFK158	Nanomolar small molecule inhibitor of PFKFB3	€90.00
3062	AZD1656	Glucokinase (GK) activator	€165.00