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Naloxone Benzoylhydrazone
- Soluble in DMSO
- MF: C26H27N3O4
- MW: 445.51
Description
Naloxone Benzoylhydrazone is an opioid receptor ligand reported as a kappa κ3 opioid receptor agonist with antagonist activity at ORL1/NOP and μ opioid receptors.
Naloxone benzoylhydrazone is useful for investigating nonclassical opioid receptor pharmacology, receptor subtype selectivity and mixed agonist-antagonist effects in opioid signaling systems.
Key Features
- Mixed opioid receptor pharmacology
- Agonist activity reported at κ3 opioid receptors
- Antagonist activity reported at ORL1/NOP and μ opioid receptors
- Useful for opioid receptor subtype profiling
Applications
- Opioid receptor functional assays
- κ opioid and NOP receptor pharmacology
- Subtype-selective ligand profiling
- Analgesia and opioid signaling studies
More Information
| Parent CAS No. | 119630-94-3 |
|---|---|
| Chemical Name | 2-[(5a)-4,5-epoxy-3,14-dihydroxy-17-(2-propenyl)morphinan-6-ylidene]hydrazide benzoic acid |
| MFCD | MFCD05662358 |
| Short Description | Kappa-opioid agonist |
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