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Fedotozine tartrate
- JO 1196
- Parent CAS: 123618-00-8
- Optical Purity: 99% e.e.
- Soluble in water
- MF: C22H31NO4.C4H6O6
- MW: 523.57
Description
Fedotozine tartrate is a peripherally-selective kappa opioid receptor (KOR) agonist with activity described at the kappa(1a) opioid receptor subtype. It is used to study kappa opioid receptor signaling and visceral pain-related pathways.
Kappa opioid receptors modulate nociception, stress responses, gastrointestinal signaling and neuroendocrine function. Fedotozine tartrate is relevant for studying peripheral kappa receptor activation and opioid receptor pharmacology.
Key Features
- Kappa opioid receptor agonist
- Activity described at kappa(1a) opioid receptors
- Useful for visceral pain and GI pathway research
- Activates kappa opioid receptor signaling
Applications
- Kappa opioid receptor pharmacology
- Visceral pain signaling studies
- Gastrointestinal sensory pathway research
- Opioid GPCR agonist assays
More Information
| Parent CAS No. | 123618-00-8 |
|---|---|
| Chemical Name | Dimethyl-[(R)-1-phenyl-1-(3,4,5-trimethoxy-benzyloxymethyl)-propyl]-amine tartrate |
| SMILES | C1(OC)C(OC)=CC(COC[C@](CC)(N(C)C)C2C=CC=CC=2)=CC=1OC.[C@@H]([C@H](O)C(O)=O)(O)C(O)=O |&1:11,27,28,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C22H31NO4.C4H6O6/c1-7-22(23(2)3,18-11-9-8-10-12-18)16-27-15-17-13-19(24-4)21(26-6)20(14-17)25-5;5-1(3(7)8)2(6)4(9)10/h8-14H,7,15-16H2,1-6H3;1-2,5-6H,(H,7,8)(H,9,10)/t22-;1-,2-/m00/s1 |
| InChiKey | DBDCBFOPBBFVQC-NNFXRGIZSA-N |
| CID | 6918159 |
| Short Description | Kappa-1a opioid agonist |
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