Bulk Inquiry
Nalbuphine hydrochloride
- Parent CAS: 20594-83-6
- Soluble in water
- MF: C21H27NO4.HCl
- MW: 393.9
Description
Nalbuphine hydrochloride is an opioid receptor modulator with κ-opioid receptor agonist activity and μ-opioid receptor antagonist/partial agonist properties.
This mixed opioid profile is relevant to analgesia with reduced μ-opioid-driven adverse effects compared with full μ agonists. Nalbuphine is useful for studying receptor-subtype contributions to analgesia, dependence liability and respiratory or CNS effects.
Key Features
- Mixed κ-opioid agonist and μ-opioid antagonist/partial agonist
- Analgesic pharmacology with subtype-selective opioid effects
- Useful for distinguishing κ- and μ-receptor contributions
- Relevant to pain and opioid safety research
Applications
- Opioid receptor subtype pharmacology
- Pain and analgesia model studies
- Kappa-opioid receptor signaling assays
- Opioid adverse-effect and dependence research
More Information
| Parent CAS No. | 20594-83-6 |
|---|---|
| Chemical Name | (–)-17-(cyclobutylmethyl)- 4,5α-epoxymorphinan- 3,6α,14-triol Hydrochloride |
| MFCD | MFCD00069325 |
| Short Description | Opioid agonist |
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