Bulk Inquiry
GNTI dihydrochloride
- 6'-Guanidinonaltrindole dihydrochloride
- Parent CAS: 219655-56-8
- Soluble in water and DMSO
- MF: C27H29N5O3.2HCl
- MW: 544.47
Description
GNTI dihydrochloride is a selective kappa (κ)-opioid receptor (KOR) antagonist derived from guanidinonaltrindole chemistry.
κ opioid receptors regulate analgesia, dysphoria, stress responsivity and reward-related signaling. GNTI is used to block κ receptor-mediated responses and to distinguish κ opioid signaling from μ and δ receptor effects.
Key Features
- Selective κ opioid receptor antagonist
- Blocks kappa opioid receptor-mediated signaling
- Useful for opioid receptor subtype discrimination
- Relevant to analgesia, stress and reward pathway research
Applications
- Kappa opioid receptor (KOR) pharmacology
- Opioid subtype selectivity assays
- Pain and analgesia model research
- Stress and reward circuitry studies
More Information
| Parent CAS No. | 219655-56-8 |
|---|---|
| Chemical Name | 5'-Guanidinyl-17-(cyclopropylmethyl)-6,7-dehydro-4,5A-epoxy-3,14-dihydroxy-6,7-2',3'-indolomorphinan dihydrochloride |
| MFCD | MFCD06795850 |
| Short Description | Kappa-opioid antagonist |
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 1140 | Fedotozine tartrate |
From $148.50 |
| 1163 | nor-Binaltorphimine dihydrochloride |
From Inquiry |
| 1202 | U-50488 hydrochloride |
From $121.00 |
| 1205 | Naloxonazine dihydrochloride |
From $154.00 |
| 1213 | β-Funaltrexamine hydrochloride |
From $104.50 |
| 1230 | Naloxone Benzoylhydrazone |
From $132.00 |
| 1412 | SNC 80 |
From $132.00 |
| 1413 | SB 612111 hydrochloride |
From $88.00 |
| 1573 | Nalmefene hydrochloride |
From $99.00 |
| 1577 | Nalbuphine hydrochloride |
From $154.00 |
| 1751 | ADL 5859 |
From $132.00 |
| 1805 | JTC 801 |
From $99.00 |
| 2415 | Naloxone hydrochloride |
From $77.00 |
| 2416 | Naltrexone hydrochloride |
From $66.00 |
| 2781 | HS666 hydrochloride |
From $148.50 |
