AM 36 dihydrochloride - CNSB002

Based on 18 reference(s) in Google Scholar 9 10 18

Axon 1113

CAS [1246094-77-8]

MF C27H39ClN2O2.2HCl
MW 531.99

Purity: 98%
Moderately soluble in water

AM 36 dihydrochloride

Description

Na+ channel blocker; neuroprotective agent.

J. K. Callaway et al. Delayed Treatment With AM-36, a Novel Neuroprotective Agent, Reduces Neuronal Damage After Endothelin-1–Induced Middle Cerebral Artery Occlusion in Conscious Rats. Stroke. 1999, 30, 2704-2712.

J. K Callaway et al. Incorporation of sodium channel blocking and free radical scavenging activities into a single drug, AM-36, results in profound inhibition of neuronal apoptosis. Br. J. Pharmacol. 2001, 132, 1691–1698.

A. Kolosov et al. Studies of synergy between morphine and a novel sodium channel blocker, CNSB002, in rat models of inflammatory and neuropathic pain. Pain Med. 2010 Jan;11(1):106-18.

Na+ channel blocker

Chemical name

2,6-Di-tert-butyl-4-{4-[2-(4-chloro-phenyl)-2-hydroxy-ethyl]-piperazin-1-ylmethyl}-phenol dihydrochloride

Parent CAS No.

[199467-52-2]

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50 mg	€545.00	In Stock

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AM 36 dihydrochloride - CNSB002

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Parent CAS No.

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AM 36 dihydrochloride - CNSB002

Description

Chemical name

Parent CAS No.

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