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Nefazodone hydrochloride
- BMY 13754
- Parent CAS: 83366-66-9
- Soluble in DMSO
- MF: C25H32ClN5O2.HCl
- MW: 506.47
Description
Antidepressant; It operates by blocking post-synaptic 5-HT2A receptors and, to a lesser extent, by inhibiting pre-synaptic serotonin and norepinephrine (noradrenaline) reuptake.
Nefazodone is also a relatively potent α1 adrenoceptor antagonist
More Information
| Parent CAS No. | 83366-66-9 |
|---|---|
| Chemical Name | 2-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propyl}-5-ethyl-4-(2-phenoxy-ethyl)-2,4-dihydro-[1,2,4]triazol-3-one hydrochloride |
| SMILES | Cl.C1(CC)N(CCOC2C=CC=CC=2)C(=O)N(CCCN2CCN(C3C=CC=C(Cl)C=3)CC2)N=1 |
| MFCD | MFCD00935760 |
| InChi | InChI=1S/C25H32ClN5O2.ClH/c1-2-24-27-31(25(32)30(24)18-19-33-23-10-4-3-5-11-23)13-7-12-28-14-16-29(17-15-28)22-9-6-8-21(26)20-22;/h3-6,8-11,20H,2,7,12-19H2,1H3;1H |
| InChiKey | DYCKFEBIOUQECE-UHFFFAOYSA-N |
| CID | 54911 |
| Short Description | Antidepressant |
References
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