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BAY 60-6583
- BR 4887
- Soluble in DMSO
- MF: C19H17N5O2S
- MW: 379.44
Description
More Information
| Parent CAS No. | 910487-58-0 |
|---|---|
| Chemical Name | 2-(6-amino-3,5-dicyano-4-(4-(cyclopropylmethoxy)phenyl)pyridin-2-ylthio)acetamide |
| SMILES | C(N)(=O)CSC1=NC(N)=C(C#N)C(C2=CC=C(OCC3CC3)C=C2)=C1C#N |
| MFCD | N.A. |
| InChi | InChI=1S/C19H17N5O2S/c20-7-14-17(12-3-5-13(6-4-12)26-9-11-1-2-11)15(8-21)19(24-18(14)23)27-10-16(22)25/h3-6,11H,1-2,9-10H2,(H2,22,25)(H2,23,24) |
| InChiKey | ZTYHZMAZUWOXNC-UHFFFAOYSA-N |
| CID | 11717831 |
| Short Description | A2B agonist |
References
- J.A. Auchampach et al. Characterization of the A2B adenosine receptor from mouse, rabbit, and dog. J Pharmacol Exp Ther. 2009 Apr;329(1):2-13.
- D. van der Hoeven et al. A role for the low-affinity A2B adenosine receptor in regulating superoxide generation by murine neutrophils. J Pharmacol Exp Ther. 2011 Sep;338(3):1004-12.
- S. Hinz et al. BAY60-6583 acts as a partial agonist at adenosine A2B receptors. J Pharmacol Exp Ther. 2014 Jun;349(3):427-36.
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