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Pritelivir
- BAY 57-1293 - AIC316
- Soluble in DMSO
- MF: C18H18N4O3S2
- MW: 402.49
Description
More Information
| Parent CAS No. | 348086-71-5 |
|---|---|
| Chemical Name | N-Methyl-N-(4-methyl-5-sulfamoylthiazol-2-yl)-2-(4-(pyridin-2-yl)phenyl)acetamide |
| SMILES | C1(CC(N(C2=NC(C)=C(S(N)(=O)=O)S2)C)=O)=CC=C(C2=NC=CC=C2)C=C1 |
| MFCD | MFCD18633192 |
| InChi | InChI=1S/C18H18N4O3S2/c1-12-17(27(19,24)25)26-18(21-12)22(2)16(23)11-13-6-8-14(9-7-13)15-5-3-4-10-20-15/h3-10H,11H2,1-2H3,(H2,19,24,25) |
| InChiKey | IVZKZONQVYTCKC-UHFFFAOYSA-N |
| CID | 491941 |
| Short Description | Helicase-primase inhibitor (HPI) |
References
- J.J. Crute et al. Herpes simplex virus helicase-primase inhibitors are active in animal models of human disease. Nat. Med. 2002, 8, 386-391.
- U.A. Betz et al. Potent in vivo antiviral activity of the herpes simplex virus primase-helicase inhibitor BAY 57-1293. Antimicrob. Agents Chemother. 2002, 46, 1766-1772.
- S. Biswas et al. The helicase primase inhibitor, BAY 57-1293 shows potent therapeutic antiviral activity superior to famciclovir in BALB/c mice infected with herpes simplex virus type 1. Antiviral Res. 2007, 75, 30-35.
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