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VU 0029767
- Soluble in DMSO
- MF: C21H21N3O3
- MW: 363.41
Description
More Information
| Parent CAS No. | 326001-01-8 |
|---|---|
| Chemical Name | 2-(4-ethoxyphenylamino)-N'-((2-hydroxynaphthalen-1-yl)methylene)acetohydrazide |
| SMILES | C(N/N=C/C1=C2C(C=CC=C2)=CC=C1O)(=O)CNC1=CC=C(OCC)C=C1 |
| MFCD | MFCD01206089 |
| InChi | InChI=1S/C21H21N3O3/c1-2-27-17-10-8-16(9-11-17)22-14-21(26)24-23-13-19-18-6-4-3-5-15(18)7-12-20(19)25/h3-13,22,25H,2,14H2,1H3,(H,24,26)/b23-13+ |
| InChiKey | JWRJGCUSLSJMMD-YDZHTSKRSA-N |
| CID | 135411347 |
| Short Description | PAM of M1 mAChR |
References
- J.E. Marlo et al. Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activity. Mol Pharmacol. 2009 Mar;75(3):577-88.
- P.J. Conn et al. Subtype-selective allosteric modulators of muscarinic receptors for the treatment of CNS disorders. Trends Pharmacol Sci. 2009 Mar;30(3):148-55.
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