MRTX1719 hydrochloride
Axon 3796
- Parent CAS: 2630904-45-7
- Optical Purity: 99% e.e.
- Soluble in water and DMSO
- MF: C23H19Cl2FN6O2
- MW: 501.34
Description
MRTX1719 is a potent and selective inhibitor of the PRMT5.MTA complex.
More Information
| Parent CAS No. | 2630904-45-7 |
|---|---|
| Chemical Name | (R)-2-(4-(4-(aminomethyl)-1-oxo-1,2-dihydrophthalazin-6-yl)-1-methyl-1H-pyrazol-5-yl)-4-chloro-6-cyclopropoxy-3-fluorobenzonitrile hydrochloride |
| extra_info | Sold in collaboration with Chemietek |
| SMILES | C1(C2=C(C3C(F)=C(Cl)C=C(OC4CC4)C=3C#N)N(C)N=C2)C=C2C(CN)=NNC(=O)C2=CC=1.Cl |&1:3,r,wU:3.3,8.7,(9.53,-8.51,;8.89,-8.14,;8.23,-8.44,;7.96,-9.38,;8.50,-9.87,;9.20,-9.64,;8.35,-10.58,;8.89,-11.07,;7.66,-10.81,;7.11,-10.32,;6.42,-10.55,;6.27,-11.26,;6.50,-11.95,;5.78,-11.80,;7.27,-9.61,;6.72,-9.12,;6.18,-8.63,;7.74,-7.90,;7.01,-7.97,;8.10,-7.26,;8.82,-7.41,;10.16,-8.14,;10.79,-8.51,;11.42,-8.14,;11.42,-7.41,;12.06,-7.05,;12.06,-8.51,;12.06,-9.24,;11.42,-9.60,;11.42,-10.33,;10.79,-9.24,;10.16,-9.60,;9.53,-9.24,;13.15,-7.04,)| |
| MFCD | N.A. |
| InChi | InChI=1S/C23H18ClFN6O2.ClH/c1-31-22(20-15(8-26)19(33-12-3-4-12)7-17(24)21(20)25)16(10-28-31)11-2-5-13-14(6-11)18(9-27)29-30-23(13)32;/h2,5-7,10,12H,3-4,9,27H2,1H3,(H,30,32);1H |
| InChiKey | DZPMMIVKBCBPMC-UHFFFAOYSA-N |
| CID | 166642550 |
| Short Description | PRMT5.MTA complex Inhibitor |
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