Bulk Inquiry
VU0360172 hydrochloride
- Parent CAS: 1310012-12-4
- Soluble in DMSO and EtOH
- MF: C18H15FN2O.HCl
- MW: 330.78
Description
VU0360172 hydrochloride is a selective, orally active mGluR5 PAM with an EC50 value of 16 nM and a Ki value of 195 nM. VU0360172 hydrochloride produced a dose-dependent reversal of amphetamine-induced hyperlocomotion, a rodent model predictive of antipsychotic activity.
More Information
| Parent CAS No. | 1310012-12-4 |
|---|---|
| Chemical Name | N-Cyclobutyl-6-((3-fluorophenyl)ethynyl)nicotinamide hydrochloride |
| SMILES | C1(F)C=C(C#CC2C=CC(C(NC3CCC3)=O)=CN=2)C=CC=1.Cl |
| MFCD | N.A. |
| InChi | InChI=1S/C18H15FN2O.ClH/c19-15-4-1-3-13(11-15)7-9-16-10-8-14(12-20-16)18(22)21-17-5-2-6-17;/h1,3-4,8,10-12,17H,2,5-6H2,(H,21,22);1H |
| InChiKey | NBGAPTWZQXSEAA-UHFFFAOYSA-N |
| CID | 53384852 |
| Short Description | mGluR5 PAM |
Related Products
| AXON ID | NAME | FROM PRICE |
|---|---|---|
| 1222 | MPEP hydrochloride |
From $82.50 |
| 1345 | Fenobam |
From $77.00 |
| 1425 | VU 29 |
From $110.00 |
| 1431 | CPPHA |
From $104.50 |
| 1739 | (RS)-3,5-DHPG |
From $99.00 |
| 1740 | (S)-3,5-DHPG |
From $99.00 |
| 1795 | VU 0360223 |
From $126.50 |
| 1894 | VU 0357121 |
From $93.50 |
| 1972 | CTEP |
From $132.00 |
| 2691 | CHPG |
From $104.50 |
| 4357 | cis-(Z)-Flupenthixol dihydrochloride |
From $143.00 |
| 4384 | (E)-Flupentixol dihydrochloride |
From $165.00 |
