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Medetomidine hydrochloride
- Parent CAS: 86347-14-0
- Soluble in water and DMSO
- MF: C13H16N2.HCl
- MW: 236.74
Description
Medetomidine hydrochloride is a potent and selective α2-adrenergic receptor agonist with Ki values of 1750 nM and 1.08 nM for the α1- and α2-adrenergic receptors, respectively. The active enantiomer, Dexmedetomidine hydrochloride (Axon 3065), is also available.
More Information
| Parent CAS No. | 86347-14-0 |
|---|---|
| Chemical Name | 4-(1-(2,3-Dimethylphenyl)ethyl)-1H-imidazole hydrochloride |
| SMILES | C(C)(C1C=CC=C(C)C=1C)C1N=CNC=1.Cl |
| MFCD | MFCD06798319 |
| InChi | InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H |
| InChiKey | VPNGEIHDPSLNMU-UHFFFAOYSA-N |
| CID | 68601 |
| Short Description | α2 agonist |
References
- H Scheinin et al. alpha 2-Adrenoceptor agonists decrease free 3-methoxy-4-hydroxyphenylglycol in rat cerebrospinal fluid. Eur J Pharmacol. 1986 Apr 9;123(1):115-21.
- R Virtanen et al. Characterization of the selectivity, specificity and potency of medetomidine as an alpha 2-adrenoceptor agonist. Eur J Pharmacol. 1988 May 20;150(1-2):9-14.
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