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Mirabegron

 - YM 178  - Betanis
Axon 2414
CAS:  223673-61-8
  • Optical Purity:  Optically pure
  • Soluble in DMSO
  • MF:  C21H24N4O2S
  • MW:  396.51

Description

Highly selective and orally active agonist of the human β3-adrenoceptor (EC50 value 22.4 nM) with >440 fold selectivity over β1, and β2. FDA approved therapeutic drug for the treatment of symptoms of overactive bladder such as urinary frequency, urgency, and urge incontinence. YM178 (Mirabegron) does not affect the amplitude of rhythmic bladder contractions at doses at which it reduces contraction frequency.

More Information

Certificate of Analysis

Material Safety Data Sheet

Parent CAS No. 223673-61-8
Chemical Name (R)-2-(2-aminothiazol-4-yl)-N-(4-(2-(2-hydroxy-2-phenylethylamino)ethyl)phenyl)acetamide
SMILES S1C=C(CC(NC2=CC=C(CCNC[C@H](O)C3=CC=CC=C3)C=C2)=O)N=C1N |&1:14,r|
MFCD N.A.
InChi InChI=1S/C21H24N4O2S/c22-21-25-18(14-28-21)12-20(27)24-17-8-6-15(7-9-17)10-11-23-13-19(26)16-4-2-1-3-5-16/h1-9,14,19,23,26H,10-13H2,(H2,22,25)(H,24,27)/t19-/m0/s1
InChiKey PBAPPPCECJKMCM-IBGZPJMESA-N
CID 9865528
Short Description β3 agonist

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