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Mirabegron
- YM 178 - Betanis- Optical Purity: Optically pure
- Soluble in DMSO
- MF: C21H24N4O2S
- MW: 396.51
Description
More Information
| Parent CAS No. | 223673-61-8 |
|---|---|
| Chemical Name | (R)-2-(2-aminothiazol-4-yl)-N-(4-(2-(2-hydroxy-2-phenylethylamino)ethyl)phenyl)acetamide |
| SMILES | S1C=C(CC(NC2=CC=C(CCNC[C@H](O)C3=CC=CC=C3)C=C2)=O)N=C1N |&1:14,r| |
| MFCD | N.A. |
| InChi | InChI=1S/C21H24N4O2S/c22-21-25-18(14-28-21)12-20(27)24-17-8-6-15(7-9-17)10-11-23-13-19(26)16-4-2-1-3-5-16/h1-9,14,19,23,26H,10-13H2,(H2,22,25)(H,24,27)/t19-/m0/s1 |
| InChiKey | PBAPPPCECJKMCM-IBGZPJMESA-N |
| CID | 9865528 |
| Short Description | β3 agonist |
References
- T. Takasu et al. Effect of (R)-2-(2-aminothiazol-4-yl)-4'-{2-[(2-hydroxy-2-phenylethyl)amino]ethyl} acetanilide (YM178), a novel selective beta3-adrenoceptor agonist, on bladder function. J Pharmacol Exp Ther. 2007 May;321(2):642-7.
- E. Sacco et al. Mirabegron: a review of recent data and its prospects in the management of overactive bladder. Ther Adv Urol. 2012 Dec;4(6):315-24.
- N. Aizawa et al. Effects of mirabegron, a novel β3-adrenoceptor agonist, on primary bladder afferent activity and bladder microcontractions in rats compared with the effects of oxybutynin. Eur Urol. 2012 Dec;62(6):1165-73.
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