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Elesclomol
- STA4783
- Soluble in 0.1N NaOH(aq), DMSO and EtOH
- MF: C19H20N4O2S2
- MW: 400.52
Description
Elesclomol is an inducer of apoptosis in cancer cells through the induction of oxidative stress. Treatment of cancer cells in vitro with Elesclomol resulted in the rapid generation of reactive oxygen species (ROS) and the induction of a transcriptional gene profile characteristic of an oxidative stress response.
More Information
| Parent CAS No. | 488832-69-5 |
|---|---|
| Chemical Name | N'1,N'3-Dimethyl-N'1,N'3-di(phenylcarbonothioyl)malonohydrazide |
| SMILES | N(N(C(=S)C1C=CC=CC=1)C)C(=O)CC(=O)NN(C(C1C=CC=CC=1)=S)C |
| MFCD | MFCD12911784 |
| InChi | InChI=1S/C19H20N4O2S2/c1-22(18(26)14-9-5-3-6-10-14)20-16(24)13-17(25)21-23(2)19(27)15-11-7-4-8-12-15/h3-12H,13H2,1-2H3,(H,20,24)(H,21,25) |
| InChiKey | BKJIXTWSNXCKJH-UHFFFAOYSA-N |
| CID | 300471 |
| Short Description | Apoptosis inducer |
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