PAZ-417 - Aleplasinin

Based on 2 reference(s) in Google Scholar 8 10 2

Axon 3710

CAS [481629-87-2]

MF C28H27NO3
MW 425.52

  • Purity: 99%
  • Soluble in DMSO and EtOH
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PAZ-417

Description

PAZ-417 is a potent, orally active and CNS-penetrant inhibitor of PAI-1 (IC50 value of 655 nM) that promotes plasmin formation and proteolysis of Aβ. In transgenic mouse models of Alzheimer’s disease, PAZ-417 reduces Aβ levels in both plasma and brain and reverses both LTP and cognitive deficits.

KEYWORDS: PAZ-417 | Supplier | PAI-1 inhibitor | Aleplasinin | PAZ417 | PAZ 417 | CAS [481629-87-2] | Serpin | Plasminogen activator inhibitor-1 (PAI-1) | Inhibitor | Enzymes | β-amyloid | Alzheimer's disease

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Size Unit Price Stock
5 mg €130.00 In Stock
25 mg €460.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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