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VU6036720 hydrochloride

Based on 1 reference(s) in Google Scholar 8 10 1

Axon 3675

CAS [N.A.]

MF C20H22ClFN4O2S.HCl
MW 473.39

  • Purity: 99%
  • Optical purity: 98.4% e.e.
  • Soluble in DMSO and EtOH

VU6036720 hydrochloride

Description

VU6036720 hydrochloride is the first potent and selective in vitro inhibitor of heteromeric Kir4.1/5.1 (KCNJ10/KCNJ16) inward rectifier potassium channels with and IC50 value of 0.24 μM.

The inactive (R)-enantiomer (Axon 3799) is also available.

KEYWORDS: VU6036720 hydrochloride | Supplier | Kir4.1/5.1 inhibitor | VU 6036720 | VU-6036720 | CAS [N.A.] | Potassium | Kir4.1 | Kir5.1 | Inhibitor | Ion Channels | Neurological and cardiovascular diseases | Kidney

First potent and selective inhibitor of heteromeric Kir4.1/5.1 inward rectifier potassium channels

Chemical name

(S)-3-Chloro-N-(2-(4-(2-cyanophenyl)-2-methylpiperazin-1-yl)ethyl)-4-fluorobenzenesulfonamide hydrochloride

Parent CAS No.

[N.A.]

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5 mg €130.00 In Stock
25 mg €450.00 In Stock
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2 x 5 mg €220.00 In Stock
2 x 25 mg €740.00 In Stock
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3799 VU6036721 hydrochloride Inactive enantiomer of VU6036720 hydrochloride €130.00

The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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