GDC-0084 - Paxalisib

Based on 23 reference(s) in Google Scholar 8 10 23

Axon 3584

CAS [1382979-44-3]

MF C18H22N8O2
MW 382.42

GDC-0084

Description

GDC-0084 is a brain-penetrant inhibitor of PI3K and mTOR with Ki (app) values of 2 nM and 0.07 μM for PI3Kα and mTOR, respectively.

Cell Signaling & Oncology mTOR PI3K-Akt-mTOR EC 2.7.11.1

Brain-penetrant dual PI3K and mTOR inhibitor

5-(6,6-Dimethyl-4-morpholino-8,9-dihydro-6H-[1,4]oxazino[3,4-e]purin-2-yl)pyrimidin-2-amine

[1382979-44-3]

Order

Size	Unit Price	Stock
5 mg	€110.00	In Stock
25 mg	€330.00	In Stock

Need more? Bulk Inquiry

Axon ID	Name	Description
1281	BEZ 235	PI3K and mTOR tyrosine kinase inhibitor	€50.00
1520	NVP-BBD130	Dual PI3K and mTOR kinase inhibitor	€125.00
1706	XL PI3K/mTOR inhibitor	Dual PI3K and mTOR kinase inhibitor	€120.00
1782	GDC 0980	Dual PI3K and mTOR inhibitor	€80.00
1807	PKI 587	Dual PI3K and mTOR inhibitor	€90.00
1855	PF 04691502	PI3K and mTOR tyrosine kinase inhibitor	€90.00
2029	NVP-BGT226	Orally active dual PI3K/mTOR inhibitor	€120.00
3628	MHY-1685	mTOR inhibitor; Senescence inhibitor	€50.00
3996	AZD2014	Orally bioavailable dual mTORC1/mTORC2 inhibitor	Inquire
4149	Everolimus	Selective and orally active mTOR1 inhibitor	Inquire