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Axon 3556
CAS [1800398-38-2]
MF C25H25F3N4O4MW 502.49
LXH254 is a potent, selective, orally available and ARAF-sparing type II inhibitor of BRAF and CRAF with IC50 values of 0.21 and 0.072 mM for BRAF and CRAF, respectively.
KEYWORDS: LXH254 | Supplier | B/C RAF inhibitor | Naporafenib | LXH 254 | LXH-254 | CAS [1800398-38-2] | MEK | RAF | Inhibitor | Enzymes | RAS mutant tumor | BRAFV600mut melanoma | MAPK-driven tumor
N-(3-(2-(2-Hydroxyethoxy)-6-morpholinopyridin-4-yl)-4-methylphenyl)-2-(trifluoromethyl)isonicotinamide
[1800398-38-2]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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