Based on 11 reference(s) in Google Scholar 8 10 11

Axon 3476

CAS [191421-10-0]

MF C13H14N2O5
MW 278.26

  • Purity: 99%
  • Optical purity: Optically pure
  • Soluble in water, DMSO and EtOH



5-NIdR, a non-natural nucleoside, is as a potent inhibitor of translesion DNA synthesis (TLS) activity. Conversion of this compound to the corresponding nucleoside triphosphate, 5-nitroindolyl-2'-deoxyriboside triphosphate, in vivo creates a potent inhibitor of several human DNA polymerases that can replicate damaged DNA.

KEYWORDS: 5-NIdR | supplier | TLS inhibitor | 5 NIdR | 5NIdR | CAS [191421-10-0] | DNA | DNA | Inhibitor | Enzymes | Acute lymphoblastic leukemia | ALL

Size Unit Price Stock
5 mg €120.00 In Stock
25 mg €420.00 In Stock
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Size Unit Price Stock
2 x 5 mg €200.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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