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MSAB
- Soluble in DMSO
- MF: C15H15NO4S
- MW: 305.35
Description
MSAB is a potent and selective inhibitor of the Wnt/β-catenin signaling pathway. MSAB shows potent anti-tumor effects selectively on Wnt-dependent cancer cells in vitro and in mouse cancer models. MSAB binds to β-catenin promoting its degradation, and specifically downregulates Wnt/β-catenin target genes.
More Information
| Parent CAS No. | 173436-66-3 |
|---|---|
| Chemical Name | Methyl 3-(4-methylphenylsulfonamido)benzoate |
| SMILES | C1(C(=O)OC)C=C(NS(=O)(=O)C2C=CC(C)=CC=2)C=CC=1 |
| MFCD | MFCD00994918 |
| InChi | InChI=1S/C15H15NO4S/c1-11-6-8-14(9-7-11)21(18,19)16-13-5-3-4-12(10-13)15(17)20-2/h3-10,16H,1-2H3 |
| InChiKey | CVKBYFCJQSPBOI-UHFFFAOYSA-N |
| CID | 1159052 |
| Short Description | Wnt/CREB inhibitor |
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