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Featured Products
Axon 3283
CAS [1619903-54-6]
MF C26H36N6OMW 448.60
LY2857785 is a highly potent and selective type I reversible and competitive ATP kinase CDK9 inhibitor with an IC50 value of 0.011 μM. LY2857785 significantly reduces RNAP II CTD phosphorylation and dramatically decreases MCL1 protein levels to result in apoptosis in a variety of leukemia and solid tumor cell lines.
KEYWORDS: LY2857785 | supplier | CDK9 inhibitor | LY 2857785 | LY-2857785 | CAS [1619903-54-6] | [1619903-55-7] | DNA-RNA | CDK9 | Inhibitor | Enzymes | Circadian clock | REV-ERBα
trans-N1-(4-(3-Isopropyl-2-methyl-2H-indazol-5-yl)pyrimidin-2-yl)-N4-(tetrahydro-2H-pyran-4-yl)cyclohexane-1,4-diamine
[1619903-54-6]
The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.
Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!
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