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Tamoxifen
- Soluble in 0.1N HCl(aq) and DMSO
- MF: C26H29NO
- MW: 371.51
Description
Tamoxifen is a first-generation selective estrogen receptor modulator (SERM).
More Information
| Parent CAS No. | 10540-29-1 |
|---|---|
| Chemical Name | (Z)-2-(4-(1,2-Diphenylbut-1-enyl)phenoxy)-N,N-dimethylethanamine |
| SMILES | C(=C(/C1C=CC=CC=1)CC)(/C1C=CC(OCCN(C)C)=CC=1)C1C=CC=CC=1 |
| MFCD | MFCD00010454 |
| InChi | InChI=1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25- |
| InChiKey | NKANXQFJJICGDU-QPLCGJKRSA-N |
| CID | 2733526 |
| Short Description | SERM |
References
- VC Jordan et al. Tamoxifen (ICI 46,474) and the human carcinoma 8S oestrogen receptor. EJ of Cancer (1965) Vol 11, Iss 3, March 1975, pp 205-206.
- BJ Furr et al. The pharmacology and clinical uses of tamoxifen. Pharmacol Ther 1984;25(2):127-205.
- PY Maximov et al. The discovery and development of selective estrogen receptor modulators (SERMs) for clinical practice. Curr Clin Pharmacol. 2013 May;8(2):135-55.
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