TAK-788 - Mobocertinib | AP32788

Based on 3 reference(s) in Google Scholar 8 10 3

Axon 3232

CAS [1847461-43-1]

MF C32H39N7O4
MW 585.70

  • Purity: 99%
  • Soluble in 0.1N HCl(aq) and DMSO
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TAK-788

Description

TAK-788 is a potent and selective dual EGFR/HER2 tyrosine kinase inhibitor. Specifically, TAK-788 inhibited all 14 mutant variants of EGFR (IC50 values between 2.4 and 22 nM), and all 6 mutant variants of HER2 (IC50 values between 2.4 and 26 nM), more potently than it inhibited WT EGFR (IC50 value of 35 nM), including all 8 variants with exon 20 activating insertions.

KEYWORDS: TAK-788 | supplier | EGFR/HER2 inhibitor | Mobocertinib | AP32788 | TAK 788 | TAK788 | AP 32788 | AP-32788 | CAS [1847461-43-1] | Non Selective (Phosphorylation Substrates) | EGFR | ErbB2-HER2 | Inhibitor | Receptors | Non-small cell lung cancer |  NSCLC

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Size Unit Price Stock
10 mg €70.00 In Stock
50 mg €210.00 In Stock
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The purity of Axon Ligands™ is confirmed by HPLC-MS, 1H-NMR and/or microanalysis. Analytical data are available upon request.

Caution: Axon Ligands™ are not fully tested. They are for research purposes only! Not for human consumption!

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