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WM-1119
- Soluble in DMSO
- MF: C18H13F2N3O3S
- MW: 389.38
Description
WM-1119 is a highly potent, selective KAT6A inhibitor with Kd and IC50 values of 0.002 μM and 0.25 µM, respectively. WM-1119 induces cell cycle exit, cellular senescence without causing DNA damage, and arrests the progression of lymphoma in mice.
More Information
| Parent CAS No. | 2055397-28-7 |
|---|---|
| Chemical Name | 2-Fluoro-N'-(3-fluoro-5-(pyridin-2-yl)benzoyl)benzenesulfonohydrazide |
| SMILES | C1C=C(F)C(S(NNC(=O)C2C=C(C3C=CC=CN=3)C=C(F)C=2)(=O)=O)=CC=1 |
| MFCD | N.A. |
| InChi | InChI=1S/C18H13F2N3O3S/c19-14-10-12(16-6-3-4-8-21-16)9-13(11-14)18(24)22-23-27(25,26)17-7-2-1-5-15(17)20/h1-11,23H,(H,22,24) |
| InChiKey | QLXULUNLCRKWRD-UHFFFAOYSA-N |
| CID | 133080719 |
| Short Description | KAT6A inhibitor |
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